Submission Date	: May,28,2015
Acceptance Date	: Jul,29,2015
Publishing Date	: Jul,31,2015
Type of Paper	: Research Article
Mode of Access	: Open Access
Author	: Ruchika Yadu1, 2, Shesh Rao Nawange1, 2*, Shankar Mohan Singh 1, 2, Ruchi Sethi Gutch 1, 2, Richa Gumasta1’2,    Mahendra Nawange2 and Arvind Kavishwar 3
Affiliation	:1. Medical Mycology Research Laboratory, Department of Biological Sciences, Rani Durgavati University, Jabalpur-482001 (M.P.) India 2. Centre for Medical Mycology, Society for Research, Diagnosis and Treatment of Human Fungal Diseases, Jabalpur-482002 (M.P.) India. 3. National Institute for Research in Tribal Health (NIRTH), Jabalpur-482003 (M. P.) India
Country	:India
Contact	:  [email protected]

Abstract

Tuberculosis kills more adults in India than any other infectious disease. Chronic nature of tubercular infection and prolonged administration of heavy doses of antibiotics not only leaves patients with an impaired or weak immunological status but also predisposes them to mycotic infection. A total of 100 pulmonary tuberculosis patients were screened, out of which 49% of total were positive for fungal infections.  The most dominant pathogens were Candida albicans 34.69% (n=17) followed by C. parapsilosis 26.53% (n=13), Aspergillus fumigatus 12.24% (n=6), A. niger 10.2% (n=5), Fusariumsolani. 6.12% (n=3), Rhizopus oryzae. 4.08% (n=2), Rhodotorulamucilaginosa. 2.04% (n=1), Geotrichum candidum 2.04% (n=1) and Myridontium keratinophylum 2.04% (n=1).  The present study revealed that 65.31% infections were due to yeasts while 37.69% infecctions were due to filamentous fungi. The coexistence of fungi with tubercle bacteria adds complication to a patient’s condition by adding more damaging and fatal dimensions to it.