Submission Date	: May  27,2015
Acceptance Date	: June 19,2015
Publishing Date	: June 30,2015
Type of Paper	: Research Article
Mode of Access	: Open Access
Author	:P.Raja Rao, Saahithi.Ch and Mallaiah. K
Affiliation	:University College of Technology, Osmania University, Hyderabad (Telangana State) 500 007
Country	:India
Contact	:  proddoku_rr@yahoo.com

Abstract

Plants have been used in traditional medicine for several thousand years. Plants have the ability to synthesize a wide variety of chemical compounds that are used to perform important biological functions. Plants can be used to treat various metabolic and genetic disorders like diabetes, cancer, cystic fibrosis and so on. Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from defect in insulin secretion, insulin action or both. One of the effective methods to control diabetes is to inhibit the activity of alpha amylase enzyme which is responsible for the breakdown of starch, thus slowing down the carbohydrate metabolism. The present study aims at finding the antihyperglycemic activity of few traditionalmedicinal plants. The plants that are chosen for the study are: Butea monosperma and Nanrdostachys jatamansi.  Soxhlet extraction experiments were performed to estimate the protein, sugar, flavonoid and phenol levels, their antibacterial activity is estimated using disc diffusion method and the antioxidant activity is estimated using the standard DPPH method. The plants have been tested for their alpha amylase enzyme inhibitory activity. The results showed that the plant extracts had good potential for the management of hyperglycemia and the related condition of oxidative stress.